Camillo Golgi (1843-1926) is widely regarded as one of the founders of modern
neuroscience. In 1873 he developed the 'reazione nera' - the black reaction...
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Résumé
Camillo Golgi (1843-1926) is widely regarded as one of the founders of modern
neuroscience. In 1873 he developed the 'reazione nera' - the black reaction - a
histological stain which was to prove to be a revolutionary method for studying the structure of the nervous system. To this day, the Golgi stain is still widely used.
For every student of medicine or biology, Golgi's name is synonymous with one of the basic structures in the cell - the Golgi apparatus, a cellular structure involved in protein glycosylation and transport. Golgi discovered the apparatus in 1898, and as a result of which, he is probably the most widely cited biologist in the scientific literature. But this is only one of Golgi's many contributions to scientific research. Amongst other things, he discovered the tendinous sensory corpuscles that bear his name - the Golgi tendon organs - and identified a type of cell in the cerebellum. He identified and described the malarial cycle in humans. His discoveries were both basic, and rich with therapeutic implications. His remarkable achievements earned him a Nobel Prize for Medicine in 1906.
It is enough to open any book of biology or medicine to realize that Golgi is one of the giants of nineteenth century scientific endeavour. Despite this, Golgi remains a relatively unknown figure in the history of neuroscience and cell biology. This long-awaited biography, in a new translation from the Italian, is a fascinating analysis of Golgi's experiments, ideas, and personal life. It will be welcomed by anyone who would like to know about this brilliant Italian scientist and his seminal contributions to, the fields of neuroscience, cytology and cell biology, pathology, and microbiology.
Sommaire
Introduction: between revolution and conservatism
From the mountains of Valcamonica to the University of Pavia
The University of Pavia Medical School before Golgi
The morphological choice
A small circle of Dante
The black silhouette
Neurohistology and neurophysiology before the "black reaction"
Finding a way out of the labyrinth
Professor at Pavia
The structure of the central nervous system
Controversies and various studies
The secret of the intermittent fevers
The prophets of the neuron
Seemingly a matter of priority
Protoplasmic pantheism
Golgi versus Cajal: holism versus reductionism at the dawn of the neurosciences
A tranquil laboratory life
The threat from Milan
The Golgi apparatus
The laboratory where a discovery is made every day